Collect all trophies
Defeat Doctor Doom with every member of the Fantastic Four
Tag in the Punisher twice while playing as Spider-Man
Team up Beast and Star-Lord
Tag in War Machine while playing as Iron Man
Tag in Pepper Potts (Rescue) while playing as Tony Stark
Beat Loki as Agent Coulson in Asgard
Beat the Green Goblin as Scarlet Spider (Classic)
Beat a Raptor as Scarlet Spider (Classic)
Beat the 3 Loki holograms as Thor in Galactus B
Complete Heroes vs. Galactus A with the Thing
Complete Stark Tower A, B and C with Hawkeye as a tag partner
Call in Daredevil with only one heart remaining
Complete Heroes vs. Galactus B with the Human Torch
Beat Doctor Octopus as Aunt May
Beat Abomination as Red Hulk
Defeat the Green Goblin as Gwen Stacy
Beat the Red Skull as Captain America and Captain America (WW2)
Beat Doctor Octopus with Human Torch in your team
Tag in Thor to battle Loki
Tag in Wolverine to finish the Abomination
100% the game
Complete all Challenges
Collect all characters
Complete Heroes vs. Galactus C with the Silver Surfer
Unlock the Creator
Collect all Red Bricks
Unlock the Future Foundation characters
Unlock all Wolverine variants
Unlock all Iron Man suits
Complete all challenges in 20 levels
Beat Iron Man (Hulkbuster) with the Hulk
Walk past Deadpool as Deadpool
Unlock all Spider-Man suits
Finish all levels
Finish Heroes vs. Galactus
Finish Asteroid M: Showdown
Finish Asteroid M: Space
Finish Island M
Finish a level as Banner
Finish New York Power Station
Finish Doctor Doom's Tanker
Finish Castle Doom
Finish X-Mansion
Finish Asgard
Finish Hydra Base
Have Captain America and Human Torch on the same screen
Finish Stark Tower
Complete all challenges in one level
Finish The Raft
Finish Oscorp
Finish Baxter Building
Finish Sand Central Station