Finish the game without using a First-Aid Spray.
Finish the game with rank S.
Finish Leech Hunter with rank E or above.
Finish Leech Hunter with rank A.
Change into a costume.
Play Leech Hunter.
Defeat Queen Leech.
Complete the treatment plant.
Obtain all keys and use them all.
Defeat the Proto Tyrant.
Complete the factory.
Fight off the Proto Tyrant.
Complete the laboratory.
Use a Green Chemical.
Defeat Mimicry Marcus with a Molotov Cocktail or a Napalm Grenade.
Defeat Infected Bat.
Defeat 16 bats in the church.
Get picked up by the Infected Bat.
Complete the training facility.
Create a Custom Handgun.
Shoot down a Hunter or an Eliminator while they are jump attacking in the air.
Defeat an enemy by burning them.
Try to push something heavy with Rebecca.
Destroy a zombie's legs.
Defeat a zombie by stomping on them.
Defeat Centurion.
Defeat an enemy with a critical-hit headshot.
Complete the train.
Break free of a Cerberus while they are biting you or trying to push you down.
Create a Molotov Cocktail.
Attack an enemy to save your partner who is grappling with that enemy.
Defeat Stinger.
Defeat an enemy with a knife.
Finish the game on Hard difficulty.
Finish the game without combining herbs.
Finish the game without saving.
Finish the game without using a recovery item (including Green Chemicals).
Defeat all bosses except Centurion using Rebecca.
Read all files.
Defeat Mimicry Marcus for the first time only using a knife.
Combine every type of herb with each other.
Obtain all weapons.
Put on Team Wesker costume.
Play the piano using Rebecca.
Collect all of only one color of Leech Charms.
Defeat all enemies in Leech Hunter.
Kill 50 enemies with the Death Stare at full charge.
