Win every trophy.
Reach Level 50 (Multiplayer Only).
Get every single bonus at least once (Multiplayer Only).
Kill your target and escape your pursuer in less than 10 seconds (Multiplayer Only).
Take the lead 10 seconds before the end of a session and go on to win (Multiplayer Only).
Get all the Co-op bonuses in 1 session (Multiplayer Only).
Perform a double or triple escape (Multiplayer Only).
During Open Conflict, kill your target and escape (Multiplayer Only).
Complete an entire Session with at least one kill (Multiplayer Only).
Score 750 points or more on a single kill (Multiplayer Only).
Kill your target while hidden in a hay bale (Multiplayer Only).
Solve all of Subject 16’s puzzles.
Jump with the parachute off the top of Castel Sant'Angelo.
Remove All Borgia Flags in Rome.
Kill a guard with a broom.
Secure the Apple of Eden.
Complete DNA Sequence 9.
Complete DNA Sequence 8.
Discover the Shrine in the Basilica di San Pietro.
Discover the Shrine in Palazzo Laterano.
Burn All Borgia Towers.
Collect All Feathers.
Discover the Shrine in the Cloaca Maxima.
Complete 10 Guild Challenges.
Win the highest bet at the Fights.
Destroy the Bomber.
Train a recruit up to the Rank of Assassin.
Complete DNA Sequence 7.
Earn 3 gold medals in the Animus Virtual Training Program.
Complete DNA Sequence 6.
Perform an Execution Streak of 10 kills.
Destroy the Tank.
Complete DNA Sequence 5.
Destroy the Naval Cannon.
Complete DNA Sequence 4.
Discover the Shrine in Il Colosseo.
Destroy the Machine Gun.
Recruit 3 Assassins.
Complete DNA Sequence 3.
Discover the Shrine in the Catacombe di Roma.
Renovate 5 buildings in the Antico district.
Find 1 Artifact in 2012.
Throw money in a well.
Achieve 100% Synchronization in any Sequence other than Sequence 1.
Replay a Memory.
Complete DNA Sequence 2.
Discover the Shrine in the Terme di Traiano.
Access your email in 2012.
Find a secure place to hide and re-enter the Animus.
Complete DNA Sequence 1.
Attempt to access DNA Sequence 9 for the first time.
Throw a Long Weapon, Heavy Weapon, and Smoke bomb more than 10 m at a guard.
Win 10000 florins playing Hazard.
Receive 100% synch in ACB and full synch in all missions of the Da Vinci Disappearance.
Kill 10 guards with a single arrow storm.
Complete the Da Vinci Disappearance.
Beat up the 5 thirsty harlequins.
Double Assassinate from a parachute.
Steal 5 horses from their riders, while remaining on horseback.
Kill a guard with the bag that drops from a lift.
Pay 500 florins to an orator, then pickpocket him afterward.