Acquire all trophies.
Complete the game with any Normal Ending.
Max out your Trust Level.
Max out your Toxicity Level.
Max out your Synergy Level.
Max out your Insight Level.
Max out your Empathy Level.
Acquire every Toxicant, Antidote, and Catalyst.
Complete the game with the Yomi Sake Bottle Ending.
Acquire every Deliriant at least once.
Defeat Hakugin.
Purchase the Yomi Sake Bottle.
Upgrade 10 total Toxicants, Antidotes, or Catalysts to Rank 5.
Reach the Fifth Circle of Hell.
Defeat White Poisonette
Clear all Belles' Hells.
Reach Level 50.
Unlock a Toxicant slot by reaching Insight Level 3.
Defeat Black Poisonette
Reach the Fourth Circle of Hell.
Upgrade one poison to Rank 5.
Reach Level 30.
Defeat 1,000 Kleshas
Reach the Third Circle of Hell.
Defeat 500 Kleshas
Unlock a skill by upgrading a poison.
Reach the Second Circle of Hell.
Reach Level 10.
Unlock a skill during a Heart-to-Heart.
Defeat 100 Kleshas
Upgrade any poison to Rank 2.
Purify your first Belle's Hell.
Have your first Heart-to-Heart.
Acquire a poison by collecting three poison gems for the first time.
Speak to your first thoughtform.
