Complete End of Zoe on Normal or Joe Must Die using no weapons.
Complete End of Zoe on Easy or Normal.
Stealth kill 5 enemies in End of Zoe.
Complete an Extreme Challenge in End of Zoe.
Perform a 4-hit combo with your bare fists in End of Zoe.
Complete the game without opening the Item Box more than 3 times.
Unlock all trophies.
Get ending 2.
Complete the game using only 3 First Aid Meds or less.
Read all of the files in a single playthrough.
Obtain all of the Antique Coins in Easy or Normal difficulty.
Kill an enemy by attaching a Remote Bomb to them and detonating it.
Watch all the videotapes in a single playthrough.
Complete the "Happy Birthday" videotape within 5 minutes.
Create all items that contain Chem Fluid and Strong Chem Fluid.
Shoot and knock back Marguerite while she's leaping at you.
Increase your item slots.
Clear insects off a door using a knife.
Avoid Jack's scissor attack by crouching.
Complete Bedroom.
Find all the dead rats in Bedroom in a single play.
Finish off an enemy with the knife.
Complete the "Mia" videotape without being spotted by Marguerite.
Get ending 1.
Complete Survival mode in 21.
Complete 21.
Get the true ending in Daughters.
Get the bad ending in Daughters.
Complete Nightmare.
Block an enemy attack by guarding.
Escape from the ship.
Escape from the Baker family home.
Uncover the secret in the old house.
Escape to the yard.
Take down two or more enemies with one shot.
Fight off Marguerite while she wanders the old house to make her run away.
Obtain all of the Antique Coins in Madhouse difficulty.
Use a lock pick to open something.
Put an unrelated object on a shadow plinth.
Obtain something by closely examining an item.
Close an open door by yourself.
Use psychostimulants.
Escape from the guest house.
Travel to Louisiana.
Complete the game within 4 hours.
Complete the game on Madhouse.
Complete the game on Normal.
Complete the game on Easy.
Destroy all Mr. Everywhere statuettes.
Destroy a Mr. Everywhere statuette.
Complete Not a Hero on Easy or Normal difficulty.
Feed Jack every type of food and drink in Jack's 55th Birthday.
Get an S Rank or higher on all stages in Jack's 55th Birthday.
Clear a stage with a 10 minute time bonus or higher in Jack's 55th Birthday.
Complete End of Zoe on Joe Must Die.
Complete Survival+ mode in 21.
Complete Ethan Must Die.
Complete Night Terror.
Complete Not a Hero on Professional difficulty.