Either Harvest or Save every Little Sister in the game.
Fully upgrade one of your Plasmids to the level 3 version at a Gatherer's Garden.
Buy one Plasmid or Tonic Slot at a Gatherer's Garden.
Install the third and final upgrade to any of your weapons.
Spend 2000 dollars at Vending Machines.
Defeat 3 Big Daddies without dying during the fight.
Research a Splicer with the Research Camera.
Successfully hack at least one of every type of machine
Upgrade any weapon at a Power to the People Station.
Earn 36 stars in the Protector Trials.
Earn an A rank in all Protector Trials
Collect 50% of the ADAM available in all Protector Trials
Earn 18 stars in the Protector Trials.
Earn 6 stars in the Protector Trials.
Collect 100% of the ADAM in a single Protector Trial
Resolve all the Little Sisters in Minerva's Den
Destroy all 10 Vacuum Bots in Minerva's Den
Kill a Lancer Big Daddy
Finish the game on the hardest difficulty level.
Finish the game without using Vita-Chambers.
Find all 14 Power to the People weapon upgrades in the game.
Find or purchase all 11 basic Plasmid types.
Fully upgrade to the maximum number of Plasmid Slots.
Max out research on all 9 research subjects.
Find 100 audio diaries.
Gather 600 ADAM with Little Sisters.
Max out one Research Track.
Get through a Gather with no damage and no one getting to the Little Sister.
Kill 30 enemies using only Traps.
Hack 30 machines at a distance with the Hack Tool.
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