Win a run with at least ten relics equipped.
Unlock all the other Trophies.
Master all relics in the original set.
Collect all relics in the original set.
Get your Attack to 1500 or higher.
Collect enough puzzle pieces to unlock a reward.
Survive to the end of a Weekly Run.
Get 5 projectiles stuck in you at once.
Insta-kill 30 enemies with Killer Joke.
Get your Max Health to 800 or higher.
Defeat the Giant Worm as the Wizard.
Get your Max Mana to 200 or higher.
Get a score of 1 million gold.
Let the Summoners complete their ritual.
Defeat a Treasure Chest Mimic on the first turn in a room.
Use each skill for each class at least once.
Defeat the Cheddar King.
Defeat the Gel Tamer.
Use skills 20 times in a room.
Defeat the Screen Fiend.
Pop 3 bubbles before you hit the bottom.
Enter the Keep with the Wizard.
Defeat the Giant Worm as the Rogue.
Level up your Hero to level 13.
Get 10 enemies to defeat each other.
Use rune stones to crack skulls.
Defeat the Organizer.
Let a lich resurrect 5 skeletons.
Get a blue trinket from the Wheel of Wonders.
Get 50 stacks of poison on an enemy at once.
Get a red trinket from the Wheel of Wonders.
Kill a Dark Elf Illusionist without hitting her mirages.
Enter the Keep with the Rogue.
Defeat the Giant Worm as the Warrior.
Defeat the Disciplinarian.
Equip a legendary item.
Clear a room without taking damage.
Use the clear Gelly Cube to cleanse a debuff.
Defeat a Chaos room.
Defeat the Goblin Poet.
Visit a treasure room.
Defeat the Cycloptopus.
Get petrified.
Help the Lonely Bard.
Get a gold trinket from the Wheel of Wonders.
Identify all the unstable potions in a run.
Intercept an Orc Shaman's healing magic.
Defeat the Alchemist.
Spend more than 2 seconds above the screen.
Complete a quest.
Defeat the Prima Ballerina.
Defeat the Under Chef.
Complete your audition.
Enter the Keep with the Warrior.
Collect all of the Treasure Hunter relics.
Master all of the Treasure Hunter relics.
Defeat the Projectionist.
Defeat the Big Freeze.
Reward the Gift Giver's generosity.
Enter the Keep with the Druid.
Defeat the Giant Worm as the Druid.
Get a score of 3 million gold.
Win a run in 90 shots or less.
Get 999 barkskin on at one time.
Get 1000 total thorn stacks in a room.
Earn 1 Encore rose.
Earn 5 Encore roses.
Earn 10 Encore roses.
Earn 15 Encore roses.
Beat Encore 5 with any hero.
Collect all of the Encore relics.
Master all of the Encore relics.
Get 35,000 gold from one potion imp.
Get a x20 scarab multiplier.
Get a score of 5 million gold.
Defeat the Mad Virologist.
Defeat the Mad Doctor.
Defeat Greg and Carl.
Defeat Bleary, Blinky, and Goo.
Defeat the Robotic Heart.
Defeat the Fungal Heart.
